Author: Cari Pérez Vives, PhD, Medical Affairs, Alcon Management (Switzerland)

Dr. Barry presented at the ESCRS congress, Barcelona 2015, the latest findings from the ESCRS EUREQUO study on FLACS (Femto Laser Assisted Cataract Surgery). This observational retrospective study was performed in 16 centres of 10 countries. The study compared femtosecond technology in 2814 cases versus manual phacoemulsification in 4918 cases. They found superior astigmatism correction in femto-second group compared to manual group, but femto-second group showed more postoperative complications than manual group, such as higher PCO rates, corneal edema and uveitis.

In the presence of these negative results for the femto-second laser technology, the role of Medical Affairs in Alcon is to understand the study and create a document to help addressing potential questions. This scientific document basically explains the limitations, their potential influence on the results of the EUREQUO study and, based on the previous scientific literature, reports contradictory results, and different views. This “barrier-handler” document is distribute internally in the company and also was presented by the training team to the product managers to enable them to discuss with the doctors in case of questions.  


Author: Alejandra Consejo, Wrocław University of Technology

The aim of this work, which hopefully will be presented in the IEEE International Symposium on Biomedical Imaging (2016, Prague), was to develop a curvature based estimator for the location of limbus, defined as the junction between cornea and sclera. Data collected from a simulated example, an artificial bi-sphere test surface and a real eye is used to validate the method. Since curvature calculation requires double differentiation of the surface under analysis and differentiation calculation greatly amplify any noise present in the data, applying regularization techniques is needed in order to control the noise effect. Different regularization techniques are tested, resulting in Deriche filtering operators that found to be the most applicable. Determining the change in the curvature of the surface of the anterior part of the eye is possible using Deriche filtering operators. This regularization technique provides accurate results for limbal demarcation. The proposed method is applied successfully on the bisphere test surface as the figure shows. The radius obtained has 0.98 % relative error. The study suggest that the shape of the limbus in the human eye is not symmetric – an important consideration in contact lens design.

Figure. Change in the curvature detection for the artificial bi-sphere. Overlapping blue asterisks indicate the registered curvature change in each meridian and yellow line indicates the fit of a circle of the points.


Author: Eleni Papadatou, University of Valencia


 During September of 2015, the ESR9 participated in two scientific congresses that both took place in Spain. The first one was the XIII Congress of the European Society of Cataract and Refractive Surgeons (ESCRS), 05/09 -09/09 in Barcelona and the second one was the International OSA Network of Students (IONS), 24/09-26/09 in Valencia.

In both events, the ESR 9 presented in front of audience different parts of her work related with optical quality of multifocal intraocular lenses (MIOLs) assessment. Moreover, ESR9 had the opportunity to interact and discuss several aspects of her work with other participants who showed interest on it.


Picture 1: ESR9 at her presentation for the International OSA Network of Students congress in Valencia.


Author: Zoulinakis Georgios, University of Valencia

The International OSA Network of Students (IONS) successfully completed its last meeting in Valencia, Spain, the weekend 24-26 September 2015. The OSA is the Optical Society interested in every field that includes optics. Between these fields is applications in Vision and Optometry.

The Optometry Research Group (GiO) from the University of Valencia was there to present different studies in the field of optometry and vision. Between these studies, Georgios Zoulinakis, from the Ageing Eye (AGEYE) program presented his poster entitled “Simulation of diffractive multifocal intraocular lenses (IOLs) with a new designing method”.

In this study a Matlab code was created in order to design diffractive mutifocal intraocular lenses. This code uses a number of points in order to design the profile of the lens and provides control of the number of the escheletes, the step height, the diffractive region radius and the function between the steps. The code provides a text file which can be introduced in optical design programs and create a simulation of this IOL in any theoretical eye model.


Author: Juan F. Zapata-Díaz, The University of Manchester.




The XIII Congress of the European Society of Cataract and Refractive Surgeons (ESCRS), one of the biggest and most important meetings in ophthalmology and vision research, took place in Barcelona from the 5th to the 9th of September of 2015.

With an attendance of more than 8000 eye care professionals and researchers, and the presentation of a massive number of studies, the meeting was a great opportunity to communicate the state-of-the-art of the vision research.

The AGEYE consortium was present at the ESCRS 2015 with a great contribution that included more than 15 communications between talks and posters, which show the advances of the project, and more than 30 collaborations in external studies.

Some of the AGEYE consortium partners present at the meeting were: The University of Valencia, The Rotterdam Ophthalmic Institute, The University of Manchester, The University of Murcia, Wroclaw University of Technology, Optegra, Alcon and Staar Surgical.

Some of the studies presented were:


- “New experimental design of phakic intraocular lens for presbyopia correction”. C. Pérez-Vives, T. Ferrer-Blasco, A. Cerviño, D. Madrid-Costa, R. Montés-Micó.

- “Myopic implatable collamer lens of -20.00 D after 5-year follow-up”. C. Pérez-Vives, C. Lisa, B. Baamonde, R. Montés-Micó, J. Alfonso.

- “Effect of daily disponsable soft contact lenses on tear film quality, assessing the higher-order aberrations after blinking”. A. Moulakaki, A. Rechioni, J. Esteve-Taboada, A. Del Águila-Carrasco, R. Montés-Micó.

- “Norm for ocular straylight of the pseudophakic eye”. G. Labuz, N. Reus, T. van den Berg.

- “A new metric for quantifying the optical quality of multifocal intraocular lenses by means of axial modulation transfer function”. E. Papadatou, A. Del Águila-Carrasco, J. Esteve-Taboada, D. Madrid-Costa, R. Montés-Micó.

- “Cataract and visual function: a prospective observational study of surgical selection”. S. Gholami, P. Aspinall, B. Dhillon, S. Klijn, N. Reus, T. van den Berg.

- “Assessment of the accommodation response over sustained near visual tasks with different electronic devices, using a Hartmann-Shack aberrometer”. A. Moulakaki, A. Rechioni, J. Esteve-Taboada, A. Del Águila-Carrasco, R. Montés-Micó.

- “Alternative method for optical design of intraocular lenses”. G. Zoulinakis, A. Moulakaki, E. Papadatou, T. Ferrer-Blasco.

- “Optical power distribution on spherical monofocal intraocular lenses”. G. Zoulinakis, E. Papadatou, A. Moulakaki, T. Ferrer-Blasco.

- “Predicting subjective depth-of-field of the accommodating eye with objective methods”. J. Zapata-Díaz, R. Iskander, N. López-Gil, J. Alfonso, H. Radhakrishnan.

- “Ocular straylight of hydrophilic and hydrophobic multifocal intraocular lenses: a literature review”. G. Labuz, N. Reus, T. van den Berg.

- “Comparison of a trifocal toric and a bifocal toric intraocular lens under simulated conditions of decentration and tilt”. E. Papadatou, G. Zoulinakis, A. Moulakaki, D. Madrid-Costa, T. Ferrer-Blasco.

- “Visual response to multifocal spherical correction”. I. Sisó-Fuertes, R. Montés-Micó, J. Alfonso, H. Radhakrishnan.